Espa?ol
PDFs by language
Our 24/7 cancer helpline provides information and answers for people dealing with cancer. We can connect you with trained cancer information specialists who will answer questions about a cancer diagnosis and provide guidance and a compassionate ear.?
Chat live online
Select the?Live?Chat button at the bottom of the page?
Call us at?1-800-227-2345
Available any time of day or night
Our highly trained specialists are available 24/7 via phone and on weekdays can assist through online chat.?We connect patients, caregivers, and family members with essential services and resources at every step of their cancer journey. Ask us how you can get involved and support the fight against cancer. Some of the topics we can assist with include:
For medical questions, we encourage you to review our information with your doctor.
Breast cancer is associated with complex genetic structures that scientists have not yet completely solved. It’s important for researchers to keep finding ways to keep identifying breast cancer-predisposing genes because that knowledge can help researchers understand disease pathways, make more personalized recommendations about screening, change guidelines for advanced genetic testing that's not routinely available, and discover new potential drug targets.?
A large international group of researchers used a recently published gene aggregation method to uncover new genes implicated in the development of breast cancer. Two of the coauthors are with the Population Science team at the American Cancer Society (快猫短视频): Lauren Teras, PhD, and Alpa Patel, PhD. They in Genome Medicine.
The team used data from the Breast Cancer Association Consortium, which has been previously studied in a variety of ways. This group, though, analyzed data that included people of non-European ancestry. “Our method enables gene discoveries that are missed by other approaches because some genetic mutations (also known as genetic variants) affecting breast cancer susceptibility vary between ancestry groups,” the authors say.
For this study, researchers analyzed genetic data from the Breast Cancer Association Consortium, which includes 83,471 breast cancer patients and 59,199 people without breast cancer. This graphic shows the 33 countries with studies that recruited participants. Of the 142,670 genetic samples, 83.4% were of European Ancestry, 10.7% were Asian, 4.1% were African, and 1.8% were of Latin American and Hispanic ancestry.
The researchers were able to replicate and extend previously reported findings, including:
?
? ??? ?
If this was helpful, donate to help fund patient support services, research, and cancer content updates.