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The American Cancer Society has issued cancer screening guidelines since 1980. ¿ìè¶ÌÊÓƵ processes and recommendations for the early detection of specific cancer types have evolved with new scientific data, as new screening technologies became available, and as standards for creating guidelines changed. The guidelines published in 1980 were based on a review of the evidence led by Dr. David Eddy, an early pioneer in evidence-based medicine. The introduction of that methodology influenced future guideline updates. The ¿ìè¶ÌÊÓƵ guidelines methodology underwent a review and update in 1997 to formalize a process that included the core stages of guideline development, implementation, and evaluation. The ¿ìè¶ÌÊÓƵ protocol included nine steps to be followed for developing or revising guidelines:

• A multidisciplinary Guideline Development Panel to oversee the process
• Defined objectives on the cancer type, target groups and how the guidelines will be used
• An outcome model which described how the guideline will influence outcomes
• A procedure for documenting the rationale for each recommendation
• Review of the scientific evidence
• Defining the specific types of evidence to be considered in the creating the guideline
• Peer review of the draft recommendation by the experts and intended user groups before publication
• Evaluation of peer review comments and creation of final guideline
• Evaluation and periodic revision of the guideline

The revised process established a more formal method for which screening recommendations for all cancer types should follow.

Although previous approaches resulted in highly credible and useful guidelines, it was recognized that the process could be improved in terms of consistency, transparency, scientific rigor, and communications. In 2011, the American Cancer Society evaluated its own process for creating cancer screening guidelines and made adjustments so its process would be more aligned with the new Institute of Medicine (IOM) standards. A?is published in the December 14, 2011 issue of the Journal of the American Medical Association. This new process implemented by the ¿ìè¶ÌÊÓƵ covers 8 principles highlighted by the IOM:

• Transparency (explaining how guidelines are created and funded)
• Conflicts of interest disclosure for those creating guidelines
• Guideline development panel of individuals with appropriate expertise in clinical screening and a patient advocate
• Independent systematic review of evidence
• Grading strength of each recommendation by explaining the level of confidence in each guideline
• Clear articulation of recommendations
• External review of the proposed guidelines from outside experts and revising as needed
• Timely updating of guidelines when there is new evidence