Espa?ol
PDFs by language
Our 24/7 cancer helpline provides information and answers for people dealing with cancer. We can connect you with trained cancer information specialists who will answer questions about a cancer diagnosis and provide guidance and a compassionate ear.?
Chat live online
Select the?Live?Chat button at the bottom of the page?
Call us at?1-800-227-2345
Available any time of day or night
Our highly trained specialists are available 24/7 via phone and on weekdays can assist through online chat.?We connect patients, caregivers, and family members with essential services and resources at every step of their cancer journey. Ask us how you can get involved and support the fight against cancer. Some of the topics we can assist with include:
For medical questions, we encourage you to review our information with your doctor.
Many studies have found that people who regularly take aspirin or another non-steroidal anti-inflammatory drug (NSAID), including ibuprofen (Advil, Motrin) and naproxen sodium (Aleve), have a lower risk for developing colorectal cancer (CRC) and polyps.
However, research results have been mixed about whether regularly taking aspirin or another NSAID helps improve the survival of people who have been diagnosed with CRC. And, not all people can safely take these medicines because of their potential for serious side effects.
Some earlier research suggested that people with CRC who took aspirin either lived just as long as those who didn’t take it, or lived a bit longer. However, a large clinical trial called the had different results.
The ASPREE trial compared people age 70 years or older who took a low-dose aspirin every day to those who took a placebo. The trial tracked them for an average of 4.7 years. The study authors reported unexpected, but statistically significant, results: the group that took the low-dose aspirin had more deaths from CRC during the years they were followed than those who took the placebo.?
Because of these conflicting studies, and because people with CRC seek guidance on what they can do to improve their prognosis, American Cancer Society (快猫短视频) scientists were motivated to further study the use of aspirin.
Peter Campbell, PhD, and his colleagues were interested in seeing aspirin’s effects in a much larger study than ASPREE. They used the 快猫短视频’s Cancer Prevention Study-II (CPS-II) Nutrition Cohort?to look at the use of aspirin and other types of NSAIDs before and after a diagnosis of CRC. They wanted to learn how aspirin might influence death from CRC for several years after diagnosis. Their results were published in
“We used responses from surveys in our CPS-II Nutrition Cohort to learn about long-term aspirin use both before and after a diagnosis of colon or rectal cancer. We found that those who reported taking aspirin at least 15 times a month before a diagnosis were less likely to die from colorectal cancer. So we looked at the data again to see if we could learn why. We found that people who regularly took aspirin before their diagnosis were less likely to have distant metastases.” –Peter Campbell, MSc, PhD
From the survey answers of men and women in the cohort who were diagnosed with CRC and could safely take aspirin, the study authors learned:
Altogether, this study suggests that for people who can safely take it, long-term, regular use of aspirin (for more than 2 years, taking 15 or more pills a month) before a diagnosis of CRC may be associated with a lower risk of being diagnosed with?metastatic CRC.?This finding is particularly important because treatment options are usually quite good for CRC that has not spread beyond the colorectum whereas treatment options are much less successful for CRC that has spread beyond the colon or rectal wall.
Apply for an 快猫短视频 Research Grant.
?
? ??? ?
If this was helpful, donate to help fund patient support services, research, and cancer content updates.