Espa?ol
PDFs by language
Our 24/7 cancer helpline provides information and answers for people dealing with cancer. We can connect you with trained cancer information specialists who will answer questions about a cancer diagnosis and provide guidance and a compassionate ear.
Chat live online
Select the Live Chat button at the bottom of the page
Call us at 1-800-227-2345
Available any time of day or night
Our highly trained specialists are available 24/7 via phone and on weekdays can assist through online chat. We connect patients, caregivers, and family members with essential services and resources at every step of their cancer journey. Ask us how you can get involved and support the fight against cancer. Some of the topics we can assist with include:
For medical questions, we encourage you to review our information with your doctor.
E-cigarettes come in lots of shapes and sizes and are known by many different names. They are also a fairly new product. People sometimes find it hard to figure out what’s in them and whether they are safe to use.
Here, we address some of the most common questions about e-cigarettes.
E-cigarettes are known by many different names. This includes e-cigs, vapes, vape pens, electronic nicotine delivery systems (ENDS), alternative nicotine delivery systems (ANDS), e-hookahs, mods, vaporizers, and tank systems. E-cigarettes are also sometimes known by their brand names.
E-cigarettes are available in many shapes and sizes. They can look like cigarettes, cigars, pipes, pens, and USB flash drives. Or they can take other forms.
All e-cigarettes include a battery that turns the device on, a heating element that heats the e-liquid and turns it into an aerosol of tiny particles (sometimes called a “vapor”), a cartridge or tank that holds the e-liquid, and a mouthpiece or opening used to inhale the aerosol.
E-cigarettes don’t have tobacco, but many of them have nicotine, which comes from tobacco. Because of this, the U.S. Food and Drug Administration (FDA) classifies them as "tobacco products."
The use of e-cigarettes is often called “vaping” because many people believe it creates a vapor that is inhaled. But in fact, e-cigarettes create an aerosol made up of tiny particles. This is different from a vapor.
E-cigarettes heat a liquid (called e-liquid, e-juice, or vape juice) and to turn it into an aerosol (sometimes called a "vapor"). When a person uses an e-cigarette, they inhale this aerosol into their lungs.
The e-liquid in most e-cigarettes has nicotine, the same addictive chemical in regular cigarettes, cigars, hookah, and other tobacco products. But nicotine levels aren’t the same in all types of e-cigarettes. Sometimes, product labels don’t list the true nicotine content.
There is evidence that nicotine harms the brain development of teenagers. If nicotine is used during pregnancy, it can also cause premature births and low birthweight babies.
There are some e-cigarette brands that have been found to contain nicotine even though they claim to be nicotine-free.
The term “vapor” might sound harmless. But the aerosol that comes out of an e-cigarette is not water vapor, and it can be harmful. The aerosol from an e-cigarette can contain nicotine and other substances that are addictive. These chemicals can also cause lung disease, heart disease, and cancer.
In addition to nicotine, e-cigarettes and e-cigarette vapor may also have these chemicals or substances:
These are considered safe if they are ingested (eaten) or applied to skin. They have not been rated as safe to breathe in, and they may cause lung irritation and allergic reactions. In some situations, they may turn into cancer-causing chemicals.
At certain levels, VOCs can cause eye, nose, and throat irritation, headaches, and nausea. They can damage the liver, kidneys, and nervous system.
One type of VOC is formaldehyde, which is known to cause cancer. Formaldehyde may form if e-liquid overheats, or if not enough liquid reaches the heating element (known as a “dry-puff”).
Some flavorings are more harmful than others. Studies show that some flavors have different levels of a chemical called diacetyl. Diacetyl has been linked to a serious lung disease called bronchiolitis obliterans, also known as popcorn lung.
The FDA does not currently require safety testing for all the substances in e-cigarettes. It's also hard to know exactly what chemicals are in an e-cigarette because most products don’t list everything that’s in them. Some products are also labeled incorrectly.
People who vape also need to check and make sure the products they buy haven’t been changed or modified. This can lead to exposure to possibly harmful or illegal substances from unknown sources and raise the risk of health problems, like lung damage.
E-cigarettes are still fairly new. More research is needed over a longer period of time before we can understand the long-term effects.
But even though the long-term health effects of e-cigarettes are not known, we do know that all tobacco products, including e-cigarettes, can pose health risks to people who use them.
For more information, see Health Risks of E-cigarettes.
No youth should use e-cigarettes or any tobacco product. This includes middle schoolers and high schoolers.
Most e-cigarettes contain addictive nicotine. Nicotine can harm the brain development of teenagers.
According to the FDA 2024 National Youth Tobacco Survey, the use of e-cigarettes dropped among middle and high schoolers during the previous year. However, there are still millions of young people using these products on an ongoing basis.
Studies also show that young people who vape are more likely to become regular users of cigarettes and other, more harmful tobacco products.
The FDA has the authority to regulate all tobacco products, including e-cigarettes. The FDA is working on several options to prevent youth access to e-cigarettes. For example, federal law prohibits the sale of any tobacco product, including e-cigarettes, to anyone who is younger than 21 years of age.
Scientists are still learning about how e-cigarettes affect health when they are used for long periods of time. It’s important to know that the aerosol ("vapor") from an e-cigarette has some cancer-causing chemicals.
There have been reports of e-cigarettes exploding and causing serious injuries. The explosions are thought to be caused by faulty batteries or because the batteries were not handled as they should be. Visit the for safety tips to help avoid an e-cigarette battery explosion.
E-cigarettes expose people to secondhand aerosol or "vapor" that can contain harmful chemicals.
Scientists are still learning about the health effects of being exposed to secondhand e-cigarette aerosol. But the U.S. Surgeon General has said that e-cigarette aerosol is not harmless. Secondhand aerosol can expose others to nicotine and possibly to other harmful chemicals.
The smoke-free and tobacco-free policies at schools, businesses, healthcare institutions, and other organizations should also cover e-cigarettes. This will help non-users avoid being exposed to potentially harmful e-cigarette aerosol.
E-cigarettes are not approved by the FDA as aids to help people stop smoking. This is because there is not enough research to show they help people stop using tobacco.
On the other hand, there are other proven methods that can help you quit using tobacco. This includes FDA-approved nicotine replacement and other medicines. There is a lot of evidence showing that these methods work. They are safe and effective, especially when combined with counseling.
Some people choose to try e-cigarettes to help them stop smoking. But e-cigarettes have as much if not more nicotine as regular cigarettes and other tobacco products.
If you switch to e-cigarettes, you will still be dealing with nicotine and other health risks. And quitting e-cigarettes is just as hard as quitting other tobacco products.
People who have switched completely from cigarettes to e-cigarettes should not switch back to smoking cigarettes (either solely or along with e-cigarettes). This could expose them to even worse health effects.
Some people who smoke use both cigarettes and e-cigarettes at the same time. This is known as “dual use.” The dual use of e-cigarettes and tobacco cigarettes can lead to significant health risks.
Recent research indicates that people who use both cigarettes and e-cigarettes have a higher risk of getting lung cancer than people who only use cigarettes.
People should not use both products at the same time and are strongly encouraged to completely stop using all tobacco products.
These resources can help you learn more about e-cigarettes:
The American Cancer Society medical and editorial content team
Our team is made up of doctors and oncology certified nurses with deep knowledge of cancer care as well as editors and translators with extensive experience in medical writing.
Banks E, Yazidjoglou A, Brown S, et al. Electronic cigarettes and health outcomes: umbrella and systematic review of the global evidence. Med J Aust. 2023;218(6):267-275. doi:10.5694/mja2.51890
Bittoni MA, Carbone DP, Harris RE (2024) Vaping, Smoking and Lung Cancer Risk. J Oncol Res Ther; 9: 10229. https://doi.org/10.29011/2574-710X.10229.
Cao DJ, Aldy K, Hsu S, et al. Review of Health Consequences of Electronic Cigarettes and the Outbreak of Electronic Cigarette, or Vaping, Product Use-Associated Lung Injury. J Med Toxicol. 2020;16(3):295-310. doi:10.1007/s13181-020-00772-w
Douglas CE, Henson R, Drope J, Wender RC. The American Cancer Society public health statement on eliminating combustible tobacco use in the United States. CA Cancer J Clin. 2018;68(4):240-245. doi:10.3322/caac.21455
Jidong, H, Duan, Z, Kwok, J, Binns S, Vera LE, Kim Y, Szczypka G, Emery SL. Vaping versus JUULing: How the Extraordinary Growth and Marketing of JUUL Transformed the US Retail e-Cigarette Market. Tobacco Control. May 2018, Accessed at https://doi.org/10.1136/tobaccocontrol-2018-054382 on November 15, 2018.
Langel SN, Kelly FL, Brass DM, et al. E-cigarette and food flavoring diacetyl alters airway cell morphology, inflammatory and antiviral response, and susceptibility to SARS-CoV-2. Cell Death Discov. 2022;8(1):64. Published 2022 Feb 15. doi:10.1038/s41420-022-00855-3
Lanspa M, Callahan SJ, Harris DL, Eve J, COllingridge D, Blagev D. Clinical presentation and outcome differences in e-cigarette or vaping product use associated lung injury (EVALIL) during the initial epidemic vs during the covid-19 pandemic. Presented at Chest 2023 of the American College of Chest Physicians; October 10, 2023; Honolulu, HI.
Liu-Zarzuela JA, Sun R. Three Seizures Provoked by E-cigarette Use in a Five-Year Period: A Case Report. Cureus. 2022;14(8):e27616. Published 2022 Aug 2. doi:10.7759/cureus.27616
Lyzwinski LN, Naslund JA, Miller CJ, Eisenberg MJ. Global youth vaping and respiratory health: epidemiology, interventions, and policies. NPJ Prim Care Respir Med. 2022;32(1):14. Published 2022 Apr 11. doi:10.1038/s41533-022-00277-9
Neczypor EW, Mears MJ, Ghosh A, et al. E-Cigarettes and Cardiopulmonary Health: Review for Clinicians. Circulation. 2022;145(3):219-232. doi:10.1161/CIRCULATIONAHA.121.056777
Owotomo O, Stritzel H, McCabe SE, Boyd CJ, Maslowsky J. Smoking Intention and Progression From E-Cigarette Use to Cigarette Smoking. Pediatrics. 2020;146(6):e2020002881. doi:10.1542/peds.2020-002881
Papaefstathiou E, Stylianou M, Agapiou A. Main and side stream effects of electronic cigarettes. J Environ Manage. 2019;238:10-17. doi:10.1016/j.jenvman.2019.01.030
Rose JJ, Krishnan-Sarin S, Exil VJ, et al. Cardiopulmonary Impact of Electronic Cigarettes and Vaping Products: A Scientific Statement From the American Heart Association. Circulation. 2023;148(8):703-728. doi:10.1161/CIR.0000000000001160
Sahu R, Shah K, Malviya R, et al. E-Cigarettes and Associated Health Risks: An Update on Cancer Potential. Adv Respir Med. 2023;91(6):516-531. Published 2023 Nov 14. doi:10.3390/arm91060038
U.S. Department of Health and Human Services, Office of the Surgeon General. E-Cigarette Use Among Youth and Young Adults: A Report of the Surgeon General. 2016.
Accessed at https://www.ncbi.nlm.nih.gov/books/NBK538680/ on October 3, 2024.
US Food and Drug Administration. Products, Ingredients & Components. Accessed at https://www.fda.gov/tobacco-products/products-guidance-regulations/products-ingredients-components on September 25, 2024.
US Food and Drug Administration. Results from the Annual National Youth Tobacco Survey. Accessed at https://www.fda.gov/tobacco-products/youth-and-tobacco/results-annual-national-youth-tobacco-survey on October 11, 2024.
Last Revised: November 19, 2024
American Cancer Society medical information is copyrighted material. For reprint requests, please see our Content Usage Policy.
Sign up to stay up-to-date with news, valuable information, and ways to get involved with the American Cancer Society.
If this was helpful, donate to help fund patient support services, research, and cancer content updates.